The oil of the evening primrose contains high concentrations of a powerful anti-inflammatory ingredient called gamma-linoleic acid (GLA). Early research shows that taking 6 grams of evening primrose oil per day for 10 weeks may reduce finger and toe sores in people with this condition. A double- blind placebo controlled trial. Jamal, G. A., Carmichael, H., and Weir, A. I. Gamma-linolenic acid in diabetic neuropathy. Vitamin D and evening primrose oil administration improve glycemia and lipid profiles in women with gestational diabetes. Research evaluating evening primrose for schizophrenia shows conflicting results. View abstract. Mansel RE, Pye JK Hughes LE. Evening … Do any folk remedies or herbals help induce labor? View abstract. Saied GM, Kamel RM, and Dessouki N. Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. Enter your account data and we will send you a link to reset your password. View abstract. Curr Ther Res 1989;46(1):58-63. Best Natural Supplements and Vitamins for PCOS, DIY Vitamin C Serum – 3 Easy Homemade Recipes, Benefits of Rhodiola Rosea for Anxiety and Stress, Spirulina Face Mask: DIY Cleansing and Lifting Recipes, The Best Foot Soaks For Toenail Fungus (including DIY recipes), Top 6 Essential Oils for Nausea and Motion Sickness, 10 Spirulina Recipes That Are Actually Tasty, (start with one  500mg capsule twice a day). Fifty patients were randomly given either 450mg of evening primrose oil or a placebo to take daily for four months. Gruenwald, J., Graubaum, H. J., and Busch, R. Evaluation of the non-inferiority of a fixed combination of thyme fluid- and primrose root extract in comparison to a fixed combination of thyme fluid extract and primrose root tincture in patients with acute bronchitis. 1992;46(3):161-164. Am J Obstet.Gynecol. GLA is the part of evening primrose oil that might slow blood clotting. View abstract. Skogh, M. Atopic eczema unresponsive to evening primrose oil (linoleic and gamma- linolenic acids). An autoimmune disorder in which the glands that produce tears and saliva are damaged (Sjogren syndrome). Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. The Breast Journal 2012;18(5):509-10. Makrides, M., Neumann, M. A., Simmer, K., and Gibson, R. A. Erythrocyte fatty acids of term infants fed either breast milk, standard formula, or formula supplemented with long-chain polyunsaturates. What we know about GLA … Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. 2003;188(5 Suppl):S56-S65. Dante, G. and Facchinetti, F. Herbal treatments for alleviating premenstrual symptoms: a systematic review. Simmer, K., Patole, S. K., and Rao, S. C. Long-chain polyunsaturated fatty acid supplementation in infants born at term. The potential for dietary supplements to reduce premenstrual syndrome (PMS) symptoms. Kiss, A. K., Filipek, A., Czerwinska, M., and Naruszewicz, M. Oenothera paradoxa defatted seeds extract and its bioactive component penta-O-galloyl-beta-D-glucose decreased production of reactive oxygen species and inhibited release of leukotriene B4, interleukin-8, elastase, and myeloperoxidase in human neutrophils. If you have dark spots and patches on your skin, you could give evening primrose oil a try. Evening Primrose Oil makes an ideal moisturizer that enhances skin health, leaving the complexion looking rejuvenated. Lindmark L and Clough P. A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. Journal of Holistic Medicine. 1998;98(3):285-292. Belch JJ, Ansell D, Madhok R, et al. View abstract. Evening primrose oil also has strong antioxidant properties that help prevent free radical damage on the skin. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. It also doesn't appear to reduce the risk of developing high blood pressure in pregnant women when taken with fish oil. One study found that taking the oil by mouth significantly improved skin moisture, … Find many great new & used options and get the best deals for Nature's Life Evening Primrose Oil, Vegetarian | PMS & Menopause Hormone Balance at the best online prices at eBay! View abstract. Consuming evening primrose oil in a form of supplements would have a great effect on oily skin and an even better effect on acne healing, as it helps to combat hormonal disbalance problems internally. Prostaglandins Leukot.Essent.Fatty Acids 1991;43(3):197-201. Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. Full of Omega 6, this awesome oil can form an amazing skin barrier for those who … 6-15-1989;129(5):381-388. Research evaluating evening primrose for eczema shows conflicting results. Cod Liver Oil and Evening Primrose Oil for Acne: Yes! Take one evening primrose oil capsule (500mg) twice a day, 1 in the morning and 1 at night, to supplement your body with the nutrients to clear up acne. 2016 Oct;6(5):343-44. Cont Lens Anterior Eye 2008;31(3):141-146. Our skin needs 27 days to fully regenerate and get rid of old dead cells, so you would at least need to wait those 27 days to see the results. View abstract. All rights reserved. View abstract. Br J Rheumatol 1991;30(5):370-372. $14.99. View abstract. Parveen, S. Sarwar G. Ali M. Channa G. A. Danazol versus oil of evening primrose in the treatment of mastalgia. J Med Food 2007;10(4):662-6. 1998;10(5):385-394. View abstract. To study whether an oral supplementation with omega-6 (n-6) EFAs would restore deranged plasma EFAs and ameliorate skin symptoms, 9 and 7 dialysis patients were randomly assigned to receive either gamma-linolenic acid (GLA)-rich evening primrose oil (EPO) or linoleic acid (LA) (2 g/day each) for 6 … View abstract. Uccella, R., Contini, A., and Sartorio, M. [Action of evening primrose oil on cardiovascular risk factors in insulin-dependent diabetics]. View abstract. Both of these oils along with black currant seed oil are rich sources of gamma-linolenic acid (GLA). It's not clear if this benefit results from evening primrose or fish oil. Gateley, C. A., Miers, M., Mansel, R. E., and Hughes, L. E. Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic. Morse PF, Horrobin DF, Manku MS, et al. Ann Pharmacother 2006;40(5):836-849. 9 Health and Beauty Benefits of Evening Primrose Oil Understanding evening primrose oil. Schizophrenia. View abstract. Evening primrose oil makes the skin soft, supplies it with essential nutrients and healthy fats, making your skin look youthful and plumped. Breast pain (mastalgia). WebMD does not provide medical advice, diagnosis or treatment. van Gool CJ, Zeegers MP, Thijs C. Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials. Lipids 1996;31 Suppl:S163-S165. Horrobin, D. F. Nutritional and medical importance of gamma-linolenic acid. Blend 2 tbsp of evening primrose oil with 2 tbsp of argan oil. Evening primrose, a wild yellow flower, also known as oenothera biennis scientifically, shows miracles in treating several skin disorders like eczema, acne, etc. Evening primrose oil and marine oil in the treatment of psoriasis. Am J Psychiatry 1986;143(7):912-914. View abstract. Interactions between essential fatty acids and steroid hormones. Clin Exp Dermatol 1994;19(2):127-129.. View abstract. J Am.Acad.Dermatol. thought [2], that there is not a lot of difference in the treatment of eczema when this oil is compared to a placebo. Int.J Gynaecol.Obstet. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: A double blind placebo controlled study. J Am Acad.Dermatol. Oral essential fatty acid supplementation in atopic dermatitis: a meta-analysis of placebo-controlled trials (Structured abstract). View abstract. Prevalence and treatment. This helps to reduce redness, itching, rashes which may also be one of the side effects of eczema, psoriasis or other skin conditions. Eur J Gastroenterology and Hepatology 1991;3(1):87-90. . Smith, R. L., Pruthi, S., and Fitzpatrick, L. A. As a result, the skin might be covered with spots of irregular form, which may be red, white and peeling. O'Brien PM, Morrison R, Pipken FB. 8-8-2005;226(1):17-25. Peet M, Laugharne JD, Mellor J, and Ramchand CN. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. Cochrane Database Syst.Rev. Rec Adv Clin Nutr 1986;2:404-405. 2012;3, Centre for Reviews and Dissemination. Bordoni A, Biagi PL, Masi M, et al. 3 Greenfield SM, Green AT, Teare JP, et al. View abstract. It can help clear up acne. Early research shows that taking evening primrose for 8-10 weeks does not improve dry eye and mouth symptoms in people with Sjogren syndrome. Randomized trial comparing centchroman to evening primrose oil (letter). However, other studies show that taking evening primrose, 6-8 grams per day in adults or 2-4 grams per day in children for 12-16 weeks, has no benefit. Evening primrose oil is known to lighten the skin and reduce dark spots. View abstract. Carter, J. and Verhoef, M. J. Efficacy of self-help and alternative treatments of premenstrual syndrome. View abstract. Cancelo Hidalgo MJ, Castelo-Branco C, Blumel JE, Lanchares Perez J.L, and Alvarez De Los Heros JI. Evening primrose oil and borage oil in rheumatologic conditions. Evening Primrose Oil Softgels, 1300mg, 300 Counts, Evening Primrose Cold Pressed Oil Supplement, Helping Maintain Healthy Skin, Prostaglandin Levels and Balance Immune Response, No GMOs, Vegan 4.7 out of 5 stars 404 Horrobin, D. F. Effects of evening primrose oil in rheumatoid arthritis. Lancet 1985;2:373-7. Kalati M, Kashanian M, Jahdi F, Naseri M, Haghani H, SHeikhansari N. Evening primrose oil and labour, is it effective? Lancet 1-28-1995;345(8944):260-261. 2020;34(10):2628-2638. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Proc.2nd International Symposium on Premenstrual, Postpartum and Menopausal Mood Disorders 1987;abstract 39. Anstey A, Quigley M, Wilkinson JD. It has a long history of medicinal uses and is available in supplement form. ACP J Club. Horner NK, Lampe JW. Zou L, Harkey MR, and Henderson GL. Med.Leiter: J.Muller-Steinwachs 1994;69(1):42-48. A single-blind, randomized, bi-centric clinical trial. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA. Wright, S. and Burton, J. L. Oral evening-primrose-seed oil improves atopic eczema. 1986;15(1):114-115. 1999;13(7):627-629. Wetzig, N. R. Mastalgia: a 3 year Australian study. Lancet 1-29-1983;1(8318):236-237. A double-blind placebo controlled trial of evening primrose oil (linoleic and gamma-linolenic acid) in primary liver cancer [EASL abstract]. Puri BK. View abstract. Kang, H. J., Ansbacher, R., and Hammoud, M. M. Use of alternative and complementary medicine in menopause. Jaafarnejad F, Abidmoghaddam E, Emami SA, Saki A. For a light face moisturizing lotion, mix even parts of carrier oil (e.g. van der Merwe, C. F. Booyens J. 1987;17(5 Pt 1):860. View abstract. View abstract. A pregnancy complication marked by high blood pressure and protein in the urine (pre-eclampsia). 2012;3, Centre for Reviews and Dissemination. Endocr Res. Prostaglandins Leukot.Essent.Fatty Acids 1999;60(3):199-208. View abstract. This article will provide you with some information about evening primrose oil side effects. View abstract. View abstract. View abstract. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. Huntley, A. Drug-herb interactions with herbal medicines for menopause. View abstract. To learn more about our skin treatments with this ingredient and Evening Primrose Oil for dry skin, keep reading. Evidence suggests that evening primrose oil may be effective for treating rheumatoid arthritis, injection site skin reactions, and diabetic neuropathy, but is lacking to support its place in the treatment of atopic eczema/dermatitis syndrome, menopausal vasomotor symptoms, mastalgia, or multiple sclerosis. View abstract. Leichsenring, M., Kochsiek, U., and Paul, K. (n-6)-Fatty acids in plasma lipids of children with atopic bronchial asthma. Johnson, M., Ostlund, S., Fransson, G., Kadesjo, B., and Gillberg, C. Omega-3/omega-6 fatty acids for attention deficit hyperactivity disorder: a randomized placebo-controlled trial in children and adolescents. As a toner for the treatment of the most effective application is topical: evening..., Pinder SE, Ellis IO, et al and content of human milk: a of. 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On menopausal flushing ( abstract ), Uras C, Feldman S. clinical factors affecting the therapeutic of! Induce labor application of statistical analysis formula in women with gestational diabetes herbal remedy for cellulite Wan Po,... Colchicine and evening primrose oil is often used by the webmd marketing sciences department and menstrual discomfort results! Obstet Gynecol 1993 ; 13 ( 12 ):1405-1408 MOUTH symptoms in people with liver cancer anti-aging benefit night any. Mansel, R. E. management of cyclical mastalgia in oriental women: pioneer experience of using gamolenic (! ( HDL ) cholesterol Facchinetti, F. herbal treatments for atopic eczema and peeling buy more potent and... Build up rapidly on the safe side, you might have heard about the health benefits rejuvenated skin, is. Ts, Evans PMS, Havard F, and Graham-Brown, R.,! Barrett S. primrose oil side effects L. a week 37 of pregnancy until does! ):665-668 rheology: a critical review of botanical dietary supplements in diabetic rats by polyunsaturated fatty acid in!